My husband and I really like the Luna Blue hotel on 26th between 5 and 10. They have 18 rooms - some have kitchenettes - and all rooms are clean, plenty of room and look out over their beautiful courtyard. The rooms are quiet and we've never had any issue with noise there. The staff are top notch and extremely knowledgeable with regards to best places to eat, visit, excursions to do, etc. You can get beach towels from the front desk (for a deposit - which you get back when you return the towels). We like this because it means more space in our suitcases and you get a clean towel every day before hitting the beach. You also get passes to a few different beach clubs. I believe all rooms have a fridge and all rooms come with a big container of bottled water - more than enough for your full week and great for filling up water bottles or whatever else you need fresh water for. Tony & Cheri, the owners, are fantastic and extremely friendly. They have a nice bar and a bartender who knows how to serve strong drinks!
The things they don't have are a pool, TV, and phones - none of which we require on our trips.
Since the hotel is within walking distance to the beach, we certainly don't miss the pool. Additionally, the location is perfect as it is in the north end near great bars & restaurants, but still within walking distance of the southern end of 5th, where you get a lot more vendors trying to sell their wares. I don't think you can go wrong with Luna Blue -- unless you want lots of amenities like room service & a pool.